What you are after is Prism, which is based on Firefox. It allows you to “split web applications out of their browser and run them directly on their desktop.” It is available for Windows, Mac and Linux
I had considerable difficulty getting Prism to work with a proxy. I ended up creating my Prism app (with icon on desktop), then editing the webapp.ini file for the Prism app (located in Documents and Settings\User\ApplicationData\WebApps) to have the URL be about:config.
Then fire up your prism app (in this case it was for Google Tasks), and edit the network.proxy settings accordingly for your network.
Close out of the prism app, and return the webapp.ini file to its previous state (url= the desired website instead of about:config).
Proxy should work now!
Prism is considered an “Inactive Project” by Mozilla.
This is the link for Chrome Application Shortcuts, which work only on Windows and Linux: https://support.google.com/chrome/answer/95710?hl=en
I use AutoHotKey to trigger some sites. I hit Win + k and my calendar opens.
#k::run "C:\Program Files (x86)\Google\Chrome\Application\chrome.exe" --app=https://www.google.com/calendar/render?pli=1